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Endoplasmic Reticulum Stress Contributes to Gefitinib-Induced Apoptosis in Glioma

Adequate stress on the Endoplasmic Reticulum (ER) with the Unfolded Protein Response (UPR) could maintain glioma malignancy. Uncontrolled ER stress, on the other hand, predisposes an apoptosis-dominant UPR program. We studied here the proapoptotic actions of the Epidermal Growth Factor Receptor (EGF...

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Detalles Bibliográficos
Autores principales: Chang, Cheng-Yi, Pan, Ping-Ho, Wu, Chih-Cheng, Liao, Su-Lan, Chen, Wen-Ying, Kuan, Yu-Hsiang, Wang, Wen-Yi, Chen, Chun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069544/
https://www.ncbi.nlm.nih.gov/pubmed/33920356
http://dx.doi.org/10.3390/ijms22083934