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Integrated Omics Strategy Reveals Cyclic Lipopeptides Empedopeptins from Massilia sp. YMA4 and Their Biosynthetic Pathway

Empedopeptins—eight amino acid cyclic lipopeptides—are calcium-dependent antibiotics that act against Gram-positive bacteria such as Staphylococcus aureus by inhibiting cell wall biosynthesis. However, to date, the biosynthetic mechanism of the empedopeptins has not been well identified. Through com...

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Detalles Bibliográficos
Autores principales: Ho, Shang-Tse, Ho, Ying-Ning, Lin, Chih, Hsu, Wei-Chen, Lee, Han-Jung, Peng, Chia-Chi, Cheng, Han-Tan, Yang, Yu-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069584/
https://www.ncbi.nlm.nih.gov/pubmed/33918939
http://dx.doi.org/10.3390/md19040209