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Novel Semi-Synthetic Cu (II)–Cardamonin Complex Exerts Potent Anticancer Activity against Triple-Negative Breast and Pancreatic Cancer Cells via Inhibition of the Akt Signaling Pathway

Cardamonin is a polyphenolic natural product that has been shown to possess cytotoxic activity against a variety of cancer cell lines. We previously reported the semi-synthesis of a novel Cu (II)–cardamonin complex (19) that demonstrated potent antitumour activity. In this study, we further investig...

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Detalles Bibliográficos
Autores principales: Hossan, Md Shahadat, Break, Mohammed Khaled Bin, Bradshaw, Tracey D., Collins, Hilary M., Wiart, Christophe, Khoo, Teng-Jin, Alafnan, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069646/
https://www.ncbi.nlm.nih.gov/pubmed/33918814
http://dx.doi.org/10.3390/molecules26082166