Genetic Screen in Adult Drosophila Reveals That dCBP Depletion in Glial Cells Mitigates Huntington Disease Pathology through a Foxo-Dependent Pathway

Huntington’s disease (HD) is a progressive and fatal autosomal dominant neurodegenerative disease caused by a CAG repeat expansion in the first exon of the huntingtin gene (HTT). In spite of considerable efforts, there is currently no treatment to stop or delay the disease. Although HTT is expressed...

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Detalles Bibliográficos
Autores principales: Martin, Elodie, Heidari, Raheleh, Monnier, Véronique, Tricoire, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069648/
https://www.ncbi.nlm.nih.gov/pubmed/33918672
http://dx.doi.org/10.3390/ijms22083884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069648/
https://www.ncbi.nlm.nih.gov/pubmed/33918672
http://dx.doi.org/10.3390/ijms22083884

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