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Rapid Decline of Serum Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) in Non-Cirrhotic Patients with Chronic Hepatitis C Infection Receiving Direct-Acting Antiviral Therapy

Direct-acting antivirals (DAAs) efficiently eradicate the hepatitis C virus (HCV). Low-density lipoprotein (LDL) levels increase rapidly upon DAA treatment. Proprotein convertase subtilisin/kexin 9 (PCSK9) induces degradation of the hepatic LDL receptor and thereby elevates serum LDL. The aim of thi...

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Detalles Bibliográficos
Autores principales: Grimm, Jonathan, Peschel, Georg, Müller, Martina, Schacherer, Doris, Wiest, Reiner, Weigand, Kilian, Buechler, Christa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069657/
https://www.ncbi.nlm.nih.gov/pubmed/33920491
http://dx.doi.org/10.3390/jcm10081621