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Anti-VEGF Drugs Influence Epigenetic Regulation and AMD-Specific Molecular Markers in ARPE-19 Cells

Our study assesses the effects of anti-VEGF (Vascular Endothelial Growth Factor) drugs and Trichostatin A (TSA), an inhibitor of histone deacetylase (HDAC) activity, on cultured ARPE-19 (Adult Retinal Pigment Epithelial-19) cells that are immortalized human retinal pigment epithelial cells. ARPE-19...

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Detalles Bibliográficos
Autores principales: Hamid, Mohamed A., Moustafa, M. Tarek, Nashine, Sonali, Costa, Rodrigo Donato, Schneider, Kevin, Atilano, Shari R., Kuppermann, Baruch D., Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069662/
https://www.ncbi.nlm.nih.gov/pubmed/33921543
http://dx.doi.org/10.3390/cells10040878