Cargando…

The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways

Endometriosis is a common gynecological disease. Here, we aimed to investigate the anti-fibrotic, anti-inflammatory, and anti-oxidative role of the methyl ester of 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO-Me) on endometriosis. An endometriosis rat model was constructed by intraperitoneall...

Descripción completa

Detalles Bibliográficos
Autores principales: Siracusa, Rosalba, D’Amico, Ramona, Cordaro, Marika, Peritore, Alessio Filippo, Genovese, Tiziana, Gugliandolo, Enrico, Crupi, Rosalia, Impellizzeri, Daniela, Cuzzocrea, Salvatore, Fusco, Roberta, Di Paola, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069675/
https://www.ncbi.nlm.nih.gov/pubmed/33924360
http://dx.doi.org/10.3390/ijms22083991