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The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways
Endometriosis is a common gynecological disease. Here, we aimed to investigate the anti-fibrotic, anti-inflammatory, and anti-oxidative role of the methyl ester of 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO-Me) on endometriosis. An endometriosis rat model was constructed by intraperitoneall...
Autores principales: | Siracusa, Rosalba, D’Amico, Ramona, Cordaro, Marika, Peritore, Alessio Filippo, Genovese, Tiziana, Gugliandolo, Enrico, Crupi, Rosalia, Impellizzeri, Daniela, Cuzzocrea, Salvatore, Fusco, Roberta, Di Paola, Rosanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069675/ https://www.ncbi.nlm.nih.gov/pubmed/33924360 http://dx.doi.org/10.3390/ijms22083991 |
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