Seed- and Soil-Dependent Differences in Murine Breast Tumor Microenvironments Dictate Anti-PD-L1 IgG Delivery and Therapeutic Efficacy

We sought to determine if Stephen Paget’s “seed and soil” hypothesis of organ-preference patterns of cancer metastasis can explain the development of heterogeneity in a tumor microenvironment (TME) as well as immunotherapeutic delivery and efficacy. We established single-cell-derived clones (clones...

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Detalles Bibliográficos
Autores principales: Liu, Yan Ting, Goel, Shreya, Kai, Megumi, Moran Guerrero, Jose Alberto, Nguyen, Thao, Mai, Junhua, Shen, Haifa, Ziemys, Arturas, Yokoi, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069710/
https://www.ncbi.nlm.nih.gov/pubmed/33920216
http://dx.doi.org/10.3390/pharmaceutics13040530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069710/
https://www.ncbi.nlm.nih.gov/pubmed/33920216
http://dx.doi.org/10.3390/pharmaceutics13040530

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