Generating New FANCA-Deficient HNSCC Cell Lines by Genomic Editing Recapitulates the Cellular Phenotypes of Fanconi Anemia

Fanconi anemia (FA) patients have an exacerbated risk of head and neck squamous cell carcinoma (HNSCC). Treatment is challenging as FA patients display enhanced toxicity to standard treatments, including radio/chemotherapy. Therefore, better therapies as well as new disease models are urgently neede...

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Detalles Bibliográficos
Autores principales: Errazquin, Ricardo, Sieiro, Esther, Moreno, Pilar, Ramirez, María José, Lorz, Corina, Peral, Jorge, Ortiz, Jessica, Casado, José Antonio, Roman-Rodriguez, Francisco J., Hanenberg, Helmut, Río, Paula, Surralles, Jordi, Segrelles, Carmen, Garcia-Escudero, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069753/
https://www.ncbi.nlm.nih.gov/pubmed/33918752
http://dx.doi.org/10.3390/genes12040548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069753/
https://www.ncbi.nlm.nih.gov/pubmed/33918752
http://dx.doi.org/10.3390/genes12040548

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