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Decitabine Promotes Modulation in Phenotype and Function of Monocytes and Macrophages That Drive Immune Response Regulation

Decitabine is an approved hypomethylating agent used for treating hematological malignancies. Although decitabine targets altered cells, epidrugs can trigger immunomodulatory effects, reinforcing the hypothesis of immunoregulation in treated patients. We therefore aimed to evaluate the impact of dec...

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Detalles Bibliográficos
Autores principales: Zambuzi, Fabiana Albani, Cardoso-Silva, Priscilla Mariane, Castro, Ricardo Cardoso, Fontanari, Caroline, Emery, Flavio da Silva, Frantz, Fabiani Gai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069756/
https://www.ncbi.nlm.nih.gov/pubmed/33921194
http://dx.doi.org/10.3390/cells10040868