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Decitabine Promotes Modulation in Phenotype and Function of Monocytes and Macrophages That Drive Immune Response Regulation
Decitabine is an approved hypomethylating agent used for treating hematological malignancies. Although decitabine targets altered cells, epidrugs can trigger immunomodulatory effects, reinforcing the hypothesis of immunoregulation in treated patients. We therefore aimed to evaluate the impact of dec...
Autores principales: | Zambuzi, Fabiana Albani, Cardoso-Silva, Priscilla Mariane, Castro, Ricardo Cardoso, Fontanari, Caroline, Emery, Flavio da Silva, Frantz, Fabiani Gai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069756/ https://www.ncbi.nlm.nih.gov/pubmed/33921194 http://dx.doi.org/10.3390/cells10040868 |
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