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Modeling Between-Subject Variability in Subcutaneous Absorption of a Fast-Acting Insulin Analogue by a Nonlinear Mixed Effects Approach

Despite the great progress made in insulin preparation and titration, many patients with diabetes are still experiencing dangerous fluctuations in their blood glucose levels. This is mainly due to the large between- and within-subject variability, which considerably hampers insulin therapy, leading...

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Detalles Bibliográficos
Autores principales: Faggionato, Edoardo, Schiavon, Michele, Dalla Man, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069884/
https://www.ncbi.nlm.nih.gov/pubmed/33921274
http://dx.doi.org/10.3390/metabo11040235