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Modeling Between-Subject Variability in Subcutaneous Absorption of a Fast-Acting Insulin Analogue by a Nonlinear Mixed Effects Approach

Despite the great progress made in insulin preparation and titration, many patients with diabetes are still experiencing dangerous fluctuations in their blood glucose levels. This is mainly due to the large between- and within-subject variability, which considerably hampers insulin therapy, leading...

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Bibliographic Details
Main Authors: Faggionato, Edoardo, Schiavon, Michele, Dalla Man, Chiara
Format: Online Article Text
Language:English
Published: MDPI 2021
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069884/
https://www.ncbi.nlm.nih.gov/pubmed/33921274
http://dx.doi.org/10.3390/metabo11040235