Low JAK2 V617F Allele Burden in Ph-Negative Chronic Myeloproliferative Neoplasms Is Associated with Additional CALR or MPL Gene Mutations

JAK2 (Janus kinase 2) V617F, CALR (Calreticulin) exon 9, and MPL (receptor for thrombopoietin) exon 10 mutations are associated with the vast majority of Ph-negative chronic myeloproliferative neoplasms (MPNs). These mutations affect sequential stages of proliferative signal transduction and therefo...

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Detalles Bibliográficos
Autores principales: Makarik, Tatiana V., Abdullaev, Adhamjon O., Nikulina, Elena E., Treglazova, Svetlana A., Stepanova, Elena E., Subortseva, Irina N., Kovrigina, Alla M., Melikyan, Anait L., Kulikov, Sergei M., Sudarikov, Andrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069892/
https://www.ncbi.nlm.nih.gov/pubmed/33921387
http://dx.doi.org/10.3390/genes12040559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069892/
https://www.ncbi.nlm.nih.gov/pubmed/33921387
http://dx.doi.org/10.3390/genes12040559

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