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A Network Medicine Approach for Drug Repurposing in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a progressive hereditary muscular disease caused by a lack of dystrophin, leading to membrane instability, cell damage, and inflammatory response. However, gene-editing alone is not enough to restore the healthy phenotype and additional treatments are required. I...

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Detalles Bibliográficos
Autores principales: Lombardo, Salvo Danilo, Basile, Maria Sofia, Ciurleo, Rosella, Bramanti, Alessia, Arcidiacono, Antonio, Mangano, Katia, Bramanti, Placido, Nicoletti, Ferdinando, Fagone, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069953/
https://www.ncbi.nlm.nih.gov/pubmed/33918694
http://dx.doi.org/10.3390/genes12040543