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A Network Medicine Approach for Drug Repurposing in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a progressive hereditary muscular disease caused by a lack of dystrophin, leading to membrane instability, cell damage, and inflammatory response. However, gene-editing alone is not enough to restore the healthy phenotype and additional treatments are required. I...
Autores principales: | Lombardo, Salvo Danilo, Basile, Maria Sofia, Ciurleo, Rosella, Bramanti, Alessia, Arcidiacono, Antonio, Mangano, Katia, Bramanti, Placido, Nicoletti, Ferdinando, Fagone, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069953/ https://www.ncbi.nlm.nih.gov/pubmed/33918694 http://dx.doi.org/10.3390/genes12040543 |
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