Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice

It is important to investigate the sex-dependent roles of microglia in pain hypersensitivity as reactive microglia within the spinal dorsal horn (DH) have been reported to be pivotal in neuropathic pain induction in male rodents upon nerve injury. Here, we aimed at determining the role of sex differ...

Descripción completa

Detalles Bibliográficos
Autores principales: Saika, Fumihiro, Matsuzaki, Shinsuke, Kishioka, Shiroh, Kiguchi, Norikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069983/
https://www.ncbi.nlm.nih.gov/pubmed/33921365
http://dx.doi.org/10.3390/cells10040874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069983/
https://www.ncbi.nlm.nih.gov/pubmed/33921365
http://dx.doi.org/10.3390/cells10040874

Ejemplares similares