Human Lanosterol 14-Alpha Demethylase (CYP51A1) Is a Putative Target for Natural Flavonoid Luteolin 7,3′-Disulfate

Widespread pathologies such as atherosclerosis, metabolic syndrome and cancer are associated with dysregulation of sterol biosynthesis and metabolism. Cholesterol modulates the signaling pathways of neoplastic transformation and tumor progression. Lanosterol 14-alpha demethylase (cytochrome P450(51)...

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Detalles Bibliográficos
Autores principales: Kaluzhskiy, Leonid, Ershov, Pavel, Yablokov, Evgeniy, Shkel, Tatsiana, Grabovec, Irina, Mezentsev, Yuri, Gnedenko, Oksana, Usanov, Sergey, Shabunya, Polina, Fatykhava, Sviatlana, Popov, Alexander, Artyukov, Aleksandr, Styshova, Olga, Gilep, Andrei, Strushkevich, Natallia, Ivanov, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070018/
https://www.ncbi.nlm.nih.gov/pubmed/33924405
http://dx.doi.org/10.3390/molecules26082237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070018/
https://www.ncbi.nlm.nih.gov/pubmed/33924405
http://dx.doi.org/10.3390/molecules26082237

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