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Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets
SIMPLE SUMMARY: All cancers must maintain telomere length to achieve immortality and around 80% do so by reactivating the enzyme complex telomerase. The diverse regulatory mechanisms surrounding the enzymatic component, telomerase reverse transcriptase (TERT), are often exploited during tumorigenesi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070023/ https://www.ncbi.nlm.nih.gov/pubmed/33924498 http://dx.doi.org/10.3390/cancers13081853 |