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Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets

SIMPLE SUMMARY: All cancers must maintain telomere length to achieve immortality and around 80% do so by reactivating the enzyme complex telomerase. The diverse regulatory mechanisms surrounding the enzymatic component, telomerase reverse transcriptase (TERT), are often exploited during tumorigenesi...

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Detalles Bibliográficos
Autores principales: Subasri, Mathushan, Shooshtari, Parisa, Watson, Andrew J., Betts, Dean H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070023/
https://www.ncbi.nlm.nih.gov/pubmed/33924498
http://dx.doi.org/10.3390/cancers13081853