Abnormal Crosstalk between Endothelial Cells and Podocytes Mediates Tyrosine Kinase Inhibitor (TKI)-Induced Nephrotoxicity

Vascular endothelial growth factor A (VEGFA) and its receptor VEGFR2 are the main targets of antiangiogenic therapies, and proteinuria is one of the common adverse events associated with the inhibition of the VEGFA/VEGFR2 pathway. The proteinuric kidney damage induced by VEGFR2 tyrosine kinase inhib...

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Detalles Bibliográficos
Autores principales: Gu, Xiaoying, Zhang, Su, Zhang, Ti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070074/
https://www.ncbi.nlm.nih.gov/pubmed/33921219
http://dx.doi.org/10.3390/cells10040869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070074/
https://www.ncbi.nlm.nih.gov/pubmed/33921219
http://dx.doi.org/10.3390/cells10040869

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