An Experimentally Induced Mutation in the UBA Domain of p62 Changes the Sensitivity of Cisplatin by Up-Regulating HK2 Localisation on the Mitochondria and Increasing Mitophagy in A2780 Ovarian Cancer Cells

The study of cisplatin sensitivity is the key to the development of ovarian cancer treatment strategies. Mitochondria are one of the main targets of cisplatin, its self-clearing ability plays an important role in determining the fate of ovarian cancer cells. First, we proved that the sensitivity of...

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Detalles Bibliográficos
Autores principales: Yu, Sihang, Yan, Xiaoyu, Tian, Rui, Xu, Long, Zhao, Yuanxin, Sun, Liankun, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070143/
https://www.ncbi.nlm.nih.gov/pubmed/33924293
http://dx.doi.org/10.3390/ijms22083983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070143/
https://www.ncbi.nlm.nih.gov/pubmed/33924293
http://dx.doi.org/10.3390/ijms22083983

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