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The YfkO Nitroreductase from Bacillus Licheniformis on Gold-Coated Superparamagnetic Nanoparticles: Towards a Novel Directed Enzyme Prodrug Therapy Approach

The bacterial nitroreductase NfnB has been the focus of a great deal of research for its use in directed enzyme prodrug therapy in combination with the nitroreductase prodrug CB1954 with this combination of enzyme and prodrug even entering clinical trials. Despite some promising results, there are m...

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Detalles Bibliográficos
Autores principales: Ball, Patrick, Hobbs, Robert, Anderson, Simon, Thompson, Emma, Gwenin, Vanessa, Von Ruhland, Christopher, Gwenin, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070144/
https://www.ncbi.nlm.nih.gov/pubmed/33918536
http://dx.doi.org/10.3390/pharmaceutics13040517