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The YfkO Nitroreductase from Bacillus Licheniformis on Gold-Coated Superparamagnetic Nanoparticles: Towards a Novel Directed Enzyme Prodrug Therapy Approach
The bacterial nitroreductase NfnB has been the focus of a great deal of research for its use in directed enzyme prodrug therapy in combination with the nitroreductase prodrug CB1954 with this combination of enzyme and prodrug even entering clinical trials. Despite some promising results, there are m...
Autores principales: | Ball, Patrick, Hobbs, Robert, Anderson, Simon, Thompson, Emma, Gwenin, Vanessa, Von Ruhland, Christopher, Gwenin, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070144/ https://www.ncbi.nlm.nih.gov/pubmed/33918536 http://dx.doi.org/10.3390/pharmaceutics13040517 |
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