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The Neuropeptide Nocistatin Is Not a Direct Agonist of Acid-Sensing Ion Channel 1a (ASIC1a)

Acid-sensing ion channels (ASICs) are ionotropic receptors that are directly activated by protons. Although protons have been shown to act as a neurotransmitter and to activate ASICs during synaptic transmission, it remains a possibility that other ligands directly activate ASICs as well. Neuropepti...

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Detalles Bibliográficos
Autores principales: Kuspiel, Sven, Wiemuth, Dominik, Gründer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070164/
https://www.ncbi.nlm.nih.gov/pubmed/33924681
http://dx.doi.org/10.3390/biom11040571