Evofosfamide Is Effective against Pediatric Aggressive Glioma Cell Lines in Hypoxic Conditions and Potentiates the Effect of Cytotoxic Chemotherapy and Ionizing Radiations

SIMPLE SUMMARY: Despite many therapeutic approaches attempted over the last years, the prognosis of children with high-grade glioma or diffuse intrinsic pontine glioma remains dismal. Hypoxia-activated prodrugs (HAPs) were developed to target hypoxic areas within solid tumors as gliomas. Evofosfamid...

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Detalles Bibliográficos
Autores principales: Bailleul, Quentin, Navarin, Pauline, Arcicasa, Mélanie, Bal-Mahieu, Christine, Carcaboso, Angel Montero, Le Bourhis, Xuefen, Furlan, Alessandro, Meignan, Samuel, Leblond, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070185/
https://www.ncbi.nlm.nih.gov/pubmed/33918823
http://dx.doi.org/10.3390/cancers13081804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070185/
https://www.ncbi.nlm.nih.gov/pubmed/33918823
http://dx.doi.org/10.3390/cancers13081804

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