Functional Characterization of Circulating Tumor Cells (CTCs) from Metastatic ER+/HER2− Breast Cancer Reveals Dependence on HER2 and FOXM1 for Endocrine Therapy Resistance and Tumor Cell Survival: Implications for Treatment of ER+/HER2− Breast Cancer

SIMPLE SUMMARY: Acquired endocrine resistance and late recurrence in patients with ER+/HER2− breast cancer are complex and not fully understood. Here, we evaluated mechanisms of acquired resistance in circulating tumor cells (CTCs) from an ER+/HER2− breast cancer patient who initially responded but...

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Detalles Bibliográficos
Autores principales: Roßwag, Sven, Cotarelo, Cristina L., Pantel, Klaus, Riethdorf, Sabine, Sleeman, Jonathan P., Schmidt, Marcus, Thaler, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070196/
https://www.ncbi.nlm.nih.gov/pubmed/33920089
http://dx.doi.org/10.3390/cancers13081810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070196/
https://www.ncbi.nlm.nih.gov/pubmed/33920089
http://dx.doi.org/10.3390/cancers13081810

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