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Role of Electrostatic Interactions in Calcitonin Prefibrillar Oligomer-Induced Amyloid Neurotoxicity and Protective Effect of Neuraminidase

Salmon calcitonin is a good model for studying amyloid behavior and neurotoxicity. Its slow aggregation rate allows the purification of low molecular weight prefibrillar oligomers, which are the most toxic species. It has been proposed that these species may cause amyloid pore formation in neuronal...

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Detalles Bibliográficos
Autores principales: Cariati, Ida, Bonanni, Roberto, Marini, Mario, Rinaldi, Anna Maria, Zarrilli, Beatrice, Tancredi, Virginia, Frank, Claudio, D’Arcangelo, Giovanna, Diociaiuti, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070249/
https://www.ncbi.nlm.nih.gov/pubmed/33920464
http://dx.doi.org/10.3390/ijms22083947