Improving the Solubility, Dissolution, and Bioavailability of Metronidazole via Cocrystallization with Ethyl Gallate

Metronidazole (MTZ) is an antibacterial drug widely used for the treatment of protozoan and anaerobic infections in humans and animals. However, its low bioavailability necessitates the frequent administration of a high dose to attain an effective plasma concentration profile for therapy. To reduce...

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Detalles Bibliográficos
Autores principales: Li, Jinhui, Hao, Xinghui, Wang, Chenguang, Liu, Haiyan, Liu, Lianchao, He, Xin, Sun, Changquan Calvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070254/
https://www.ncbi.nlm.nih.gov/pubmed/33919704
http://dx.doi.org/10.3390/pharmaceutics13040546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070254/
https://www.ncbi.nlm.nih.gov/pubmed/33919704
http://dx.doi.org/10.3390/pharmaceutics13040546

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