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Improving the Solubility, Dissolution, and Bioavailability of Metronidazole via Cocrystallization with Ethyl Gallate
Metronidazole (MTZ) is an antibacterial drug widely used for the treatment of protozoan and anaerobic infections in humans and animals. However, its low bioavailability necessitates the frequent administration of a high dose to attain an effective plasma concentration profile for therapy. To reduce...
Autores principales: | Li, Jinhui, Hao, Xinghui, Wang, Chenguang, Liu, Haiyan, Liu, Lianchao, He, Xin, Sun, Changquan Calvin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070254/ https://www.ncbi.nlm.nih.gov/pubmed/33919704 http://dx.doi.org/10.3390/pharmaceutics13040546 |
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