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Endogenous H(2)O(2)-Sensitive and Weak Acidic pH-Triggered Nitrogen-Doped Graphene Nanoparticles (N-GNMs) in the Tumor Microenvironment Serve as Peroxidase-Mimicking Nanozymes for Tumor-Specific Treatment

Nanozymes are emerging as a promising strategy for the treatment of tumors. Herein, to cope with the tumor microenvironment (TME), weak acidity (pH 5.6 to 6.8) and trace amounts of overexpressed hydrogen peroxide (H(2)O(2)) (100 µM–1 mM), we report nitrogen-doped graphene nanomaterials (N-GNMs), whi...

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Detalles Bibliográficos
Autores principales: Liang, Danyang, Yang, Yongzhen, Li, Gongjian, Wang, Qin, Chen, Heting, Deng, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070265/
https://www.ncbi.nlm.nih.gov/pubmed/33924339
http://dx.doi.org/10.3390/ma14081933