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α-Tocopherol Attenuates Oxidative Phosphorylation of CD34(+) Cells, Enhances Their G0 Phase Fraction and Promotes Hematopoietic Stem and Primitive Progenitor Cell Maintenance

Alpha tocopherol acetate (αTOA) is an analogue of alpha tocopherol (αTOC) that exists in the form of an injectable drug. In the context of the metabolic hypothesis of stem cells, we studied the impact of αTOA on the metabolic energetic profile and functional properties of hematopoietic stem and prog...

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Detalles Bibliográficos
Autores principales: Rodriguez, Laura, Duchez, Pascale, Touya, Nicolas, Debeissat, Christelle, Guitart, Amélie V., Pasquet, Jean-Max, Vlaski-Lafarge, Marija, Brunet de la Grange, Philippe, Ivanovic, Zoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070309/
https://www.ncbi.nlm.nih.gov/pubmed/33920203
http://dx.doi.org/10.3390/biom11040558