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Melatonin Modulates the Antioxidant Defenses and the Expression of Proinflammatory Mediators in Pancreatic Stellate Cells Subjected to Hypoxia

Pancreatic stellate cells (PSC) play a major role in the formation of fibrotic tissue in pancreatic tumors. On its side, melatonin is a putative therapeutic agent for pancreatic cancer and inflammation. In this work, the actions of melatonin on PSC subjected to hypoxia were evaluated. Reactive oxyge...

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Detalles Bibliográficos
Autores principales: Estaras, Matias, Gonzalez-Portillo, Manuel R., Martinez, Remigio, Garcia, Alfredo, Estevez, Mario, Fernandez-Bermejo, Miguel, Mateos, Jose M., Vara, Daniel, Blanco-Fernández, Gerardo, Lopez-Guerra, Diego, Roncero, Vicente, Salido, Gines M., Gonzalez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070371/
https://www.ncbi.nlm.nih.gov/pubmed/33918063
http://dx.doi.org/10.3390/antiox10040577