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Melatonin Modulates the Antioxidant Defenses and the Expression of Proinflammatory Mediators in Pancreatic Stellate Cells Subjected to Hypoxia
Pancreatic stellate cells (PSC) play a major role in the formation of fibrotic tissue in pancreatic tumors. On its side, melatonin is a putative therapeutic agent for pancreatic cancer and inflammation. In this work, the actions of melatonin on PSC subjected to hypoxia were evaluated. Reactive oxyge...
Autores principales: | Estaras, Matias, Gonzalez-Portillo, Manuel R., Martinez, Remigio, Garcia, Alfredo, Estevez, Mario, Fernandez-Bermejo, Miguel, Mateos, Jose M., Vara, Daniel, Blanco-Fernández, Gerardo, Lopez-Guerra, Diego, Roncero, Vicente, Salido, Gines M., Gonzalez, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070371/ https://www.ncbi.nlm.nih.gov/pubmed/33918063 http://dx.doi.org/10.3390/antiox10040577 |
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