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Monoclonal Antibody Aggregation Associated with Free Radical Induced Oxidation

Oxidation is an important degradation pathway of protein drugs. The susceptibility to oxidation is a common concern for therapeutic proteins as it may impact product efficacy and patient safety. In this work, we used 2,2′-azobis (2-amidinopropane) dihydrochloride (AAPH) as an oxidative stress reagen...

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Detalles Bibliográficos
Autores principales:	Zheng, Kai, Ren, Diya, Wang, Y. John, Lilyestrom, Wayne, Scherer, Thomas, Hong, Justin K. Y., Ji, Junyan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070435/ https://www.ncbi.nlm.nih.gov/pubmed/33921206 http://dx.doi.org/10.3390/ijms22083952

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