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DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation

A common pathological hallmark of several neurodegenerative diseases, including amyotrophic lateral sclerosis, is cytoplasmic mislocalization and aggregation of nuclear RNA-binding protein TDP-43. Perry disease, which displays inherited atypical parkinsonism, is a type of TDP-43 proteinopathy. The c...

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Detalles Bibliográficos
Autores principales: Deshimaru, Manami, Kinoshita-Kawada, Mariko, Kubota, Kaori, Watanabe, Takuya, Tanaka, Yasuyoshi, Hirano, Saito, Ishidate, Fumiyoshi, Hiramoto, Masaki, Ishikawa, Mitsuru, Uehara, Yoshinari, Okano, Hideyuki, Hirose, Shinichi, Fujioka, Shinsuke, Iwasaki, Katsunori, Yuasa-Kawada, Junichi, Mishima, Takayasu, Tsuboi, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070438/
https://www.ncbi.nlm.nih.gov/pubmed/33924373
http://dx.doi.org/10.3390/ijms22083985