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Engineered Human Heavy-Chain Ferritin with Half-Life Extension and Tumor Targeting by PAS and RGDK Peptide Functionalization

Ferritin, one of the most investigated protein nanocages, is considered as a promising drug carrier because of its advantageous stability and safety. However, its short half-life and undesirable tumor targeting ability has limited its usage in tumor treatment. In this work, two types of functional p...

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Detalles Bibliográficos
Autores principales: Yin, Shuang, Wang, Yan, Zhang, Bingyang, Qu, Yiran, Liu, Yongdong, Dai, Sheng, Zhang, Yao, Wang, Yingli, Bi, Jingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070472/
https://www.ncbi.nlm.nih.gov/pubmed/33918853
http://dx.doi.org/10.3390/pharmaceutics13040521