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Engineered Human Heavy-Chain Ferritin with Half-Life Extension and Tumor Targeting by PAS and RGDK Peptide Functionalization
Ferritin, one of the most investigated protein nanocages, is considered as a promising drug carrier because of its advantageous stability and safety. However, its short half-life and undesirable tumor targeting ability has limited its usage in tumor treatment. In this work, two types of functional p...
Autores principales: | Yin, Shuang, Wang, Yan, Zhang, Bingyang, Qu, Yiran, Liu, Yongdong, Dai, Sheng, Zhang, Yao, Wang, Yingli, Bi, Jingxiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070472/ https://www.ncbi.nlm.nih.gov/pubmed/33918853 http://dx.doi.org/10.3390/pharmaceutics13040521 |
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