Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material

The world-first success of lipid nanoparticle (LNP)-based siRNA therapeutics (ONPATTRO(®)) promises to accelerate developments in siRNA therapeutics/gene therapy using LNP-type drug delivery systems (DDS). In this study, we explore the optimal composition of an LNP containing a self-degradable mater...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiroki, Takata, Nae, Sakurai, Yu, Yoshida, Tokuyuki, Inoue, Takao, Tamagawa, Shinya, Nakai, Yuta, Tange, Kota, Yoshioka, Hiroki, Maeki, Masatoshi, Tokeshi, Manabu, Akita, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070490/
https://www.ncbi.nlm.nih.gov/pubmed/33924589
http://dx.doi.org/10.3390/pharmaceutics13040544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070490/
https://www.ncbi.nlm.nih.gov/pubmed/33924589
http://dx.doi.org/10.3390/pharmaceutics13040544

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