GSK-3α Inhibition in Drug-Resistant CML Cells Promotes Susceptibility to NK Cell-Mediated Lysis in an NKG2D- and NKp30-Dependent Manner

SIMPLE SUMMARY: Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase that has gained considerable interest as a therapeutic target for cancer due to its key involvement in growth arrest and apoptosis of tumor cells. Moreover, GSK-3, especially GSK-3β, limits the activation of NK c...

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Detalles Bibliográficos
Autores principales: Kim, Nayoung, Kim, Mi Yeon, Choi, Woo Seon, Yi, Eunbi, Lee, Hyo Jung, Kim, Hun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070516/
https://www.ncbi.nlm.nih.gov/pubmed/33918810
http://dx.doi.org/10.3390/cancers13081802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070516/
https://www.ncbi.nlm.nih.gov/pubmed/33918810
http://dx.doi.org/10.3390/cancers13081802

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