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A Label-Free DNA-Immunosensor Based on Aminated rGO Electrode for the Quantification of DNA Methylation

In this work, we developed a sandwich DNA-immunosensor for quantification of the methylated tumour suppressor gene O-6-methylguanine-DNA methyltransferase (MGMT), which is a potential biomarker for brain tumours and breast cancer. The biosensor is based on aminated reduced graphene oxide electrode,...

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Detalles Bibliográficos
Autores principales: Safarzadeh, Mina, Suhail, Ahmed, Sethi, Jagriti, Sattar, Anas, Jenkins, David, Pan, Genhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070590/
https://www.ncbi.nlm.nih.gov/pubmed/33921234
http://dx.doi.org/10.3390/nano11040985