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AKT Inhibitors: The Road Ahead to Computational Modeling-Guided Discovery
AKT, is a serine/threonine protein kinase comprising three isoforms—namely: AKT1, AKT2 and AKT3, whose inhibitors have been recognized as promising therapeutic targets for various human disorders, especially cancer. In this work, we report a systematic evaluation of multi-target Quantitative Structu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070654/ https://www.ncbi.nlm.nih.gov/pubmed/33920446 http://dx.doi.org/10.3390/ijms22083944 |