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AKT Inhibitors: The Road Ahead to Computational Modeling-Guided Discovery

AKT, is a serine/threonine protein kinase comprising three isoforms—namely: AKT1, AKT2 and AKT3, whose inhibitors have been recognized as promising therapeutic targets for various human disorders, especially cancer. In this work, we report a systematic evaluation of multi-target Quantitative Structu...

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Detalles Bibliográficos
Autores principales: Halder, Amit Kumar, Cordeiro, M. Natália D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070654/
https://www.ncbi.nlm.nih.gov/pubmed/33920446
http://dx.doi.org/10.3390/ijms22083944