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Role of cAMP in Double Switch of Glucagon Secretion

Glucose metabolism plays a crucial role in modulating glucagon secretion in pancreatic alpha cells. However, the downstream effects of glucose metabolism and the activated signaling pathways influencing glucagon granule exocytosis are still obscure. We developed a computational alpha cell model, imp...

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Detalles Bibliográficos
Autores principales: Zmazek, Jan, Grubelnik, Vladimir, Markovič, Rene, Marhl, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070687/
https://www.ncbi.nlm.nih.gov/pubmed/33919776
http://dx.doi.org/10.3390/cells10040896