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Role of cAMP in Double Switch of Glucagon Secretion
Glucose metabolism plays a crucial role in modulating glucagon secretion in pancreatic alpha cells. However, the downstream effects of glucose metabolism and the activated signaling pathways influencing glucagon granule exocytosis are still obscure. We developed a computational alpha cell model, imp...
Autores principales: | Zmazek, Jan, Grubelnik, Vladimir, Markovič, Rene, Marhl, Marko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070687/ https://www.ncbi.nlm.nih.gov/pubmed/33919776 http://dx.doi.org/10.3390/cells10040896 |
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