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New Insights into the Multifaceted Role of Myeloid-Derived Suppressor Cells (MDSCs) in High-Grade Gliomas: From Metabolic Reprograming, Immunosuppression, and Therapeutic Resistance to Current Strategies for Targeting MDSCs

Cancer cells “hijack” host immune cells to promote growth, survival, and metastasis. The immune microenvironment of high-grade gliomas (HGG) is a complex and heterogeneous system, consisting of diverse cell types such as microglia, bone marrow-derived macrophages (BMDMs), myeloid-derived suppressor...

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Detalles Bibliográficos
Autores principales: Lakshmanachetty, Senthilnath, Cruz-Cruz, Joselyn, Hoffmeyer, Eric, Cole, Allison P., Mitra, Siddhartha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070707/
https://www.ncbi.nlm.nih.gov/pubmed/33919732
http://dx.doi.org/10.3390/cells10040893