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Standing Variations Modeling Captures Inter-Individual Heterogeneity in a Deterministic Model of Prostate Cancer Response to Combination Therapy

SIMPLE SUMMARY: Studying rare outcomes in cancer is challenging because observation of the rare event may require a very high number of patients or experimental animals. Here, we propose a new, predictive approach to understanding the biological mechanisms underlying such rare events in cancer treat...

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Detalles Bibliográficos
Autores principales: Jain, Harsh Vardhan, Sorribes, Inmaculada C., Handelman, Samuel K., Barnaby, Johnna, Jackson, Trachette L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070719/
https://www.ncbi.nlm.nih.gov/pubmed/33919753
http://dx.doi.org/10.3390/cancers13081872