Mutations Q93H and E97K in TPM2 Disrupt Ca-Dependent Regulation of Actin Filaments

Tropomyosin is a two-chain coiled coil protein, which together with the troponin complex controls interactions of actin with myosin in a Ca(2+)-dependent manner. In fast skeletal muscle, the contractile actin filaments are regulated by tropomyosin isoforms Tpm1.1 and Tpm2.2, which form homo- and het...

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Detalles Bibliográficos
Autores principales: Śliwinska, Małgorzata, Robaszkiewicz, Katarzyna, Wasąg, Piotr, Moraczewska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070786/
https://www.ncbi.nlm.nih.gov/pubmed/33919826
http://dx.doi.org/10.3390/ijms22084036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070786/
https://www.ncbi.nlm.nih.gov/pubmed/33919826
http://dx.doi.org/10.3390/ijms22084036

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