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Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium

The HIF prolyl 4-hydroxylases (HIF-P4H) control hypoxia-inducible factor (HIF), a powerful mechanism regulating cellular adaptation to decreased oxygenation. The gastrointestinal epithelium subsists in “physiological hypoxia” and should therefore have an especially well-designed control over this ad...

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Detalles Bibliográficos
Autores principales: Dengler, Franziska, Sova, Sofia, Salo, Antti M., Mäki, Joni M., Koivunen, Peppi, Myllyharju, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070794/
https://www.ncbi.nlm.nih.gov/pubmed/33919829
http://dx.doi.org/10.3390/ijms22084038