Molecular Simulation-Based Investigation of Highly Potent Natural Products to Abrogate Formation of the nsp10–nsp16 Complex of SARS-CoV-2

The SARS-CoV-2 non-structural protein (nsp) nsp10–nsp16 complex is essential for the 2′-O-methylation of viral mRNA, a crucial step for evading the innate immune system, and it is an essential process in SARS-CoV-2 life cycle. Therefore, detecting molecules that can disrupt the nsp10–nsp16 interacti...

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Detalles Bibliográficos
Autores principales: Mohammad, Anwar, Alshawaf, Eman, Marafie, Sulaiman K., Abu-Farha, Mohamed, Al-Mulla, Fahd, Abubaker, Jehad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070809/
https://www.ncbi.nlm.nih.gov/pubmed/33919870
http://dx.doi.org/10.3390/biom11040573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070809/
https://www.ncbi.nlm.nih.gov/pubmed/33919870
http://dx.doi.org/10.3390/biom11040573

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