Integrating neuroimaging biomarkers into the multicentre, high-dose erythropoietin for asphyxia and encephalopathy (HEAL) trial: rationale, protocol and harmonisation

INTRODUCTION: MRI and MR spectroscopy (MRS) provide early biomarkers of brain injury and treatment response in neonates with hypoxic-ischaemic encephalopathy). Still, there are challenges to incorporating neuroimaging biomarkers into multisite randomised controlled trials. In this paper, we provide...

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Detalles Bibliográficos
Autores principales: Wisnowski, Jessica L, Bluml, Stefan, Panigrahy, Ashok, Mathur, Amit M, Berman, Jeffrey, Chen, Ping-Sun Keven, Dix, James, Flynn, Trevor, Fricke, Stanley, Friedman, Seth D, Head, Hayden W, Ho, Chang Y, Kline-Fath, Beth, Oveson, Michael, Patterson, Richard, Pruthi, Sumit, Rollins, Nancy, Ramos, Yanerys M, Rampton, John, Rusin, Jerome, Shaw, Dennis W, Smith, Mark, Tkach, Jean, Vasanawala, Shreyas, Vossough, Arastoo, Whitehead, Matthew T, Xu, Duan, Yeom, Kristen, Comstock, Bryan, Heagerty, Patrick J, Juul, Sandra E, Wu, Yvonne W, McKinstry, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070884/
https://www.ncbi.nlm.nih.gov/pubmed/33888528
http://dx.doi.org/10.1136/bmjopen-2020-043852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070884/
https://www.ncbi.nlm.nih.gov/pubmed/33888528
http://dx.doi.org/10.1136/bmjopen-2020-043852

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