Nicorandil attenuates high glucose-induced insulin resistance by suppressing oxidative stress-mediated ER stress PERK signaling pathway

INTRODUCTION: Glucose-induced insulin resistance is a typical character of diabetes. Nicorandil is now widely used in ischemic heart disease. Nicorandil shows protective effects against oxidative and endoplasmic reticulum (ER) stress, which are involved in insulin resistance. Here, we investigated m...

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Detalles Bibliográficos
Autores principales: Liu, Zhongwei, Zhu, Haitao, He, Chunhui, He, Ting, Pan, Shuo, Zhao, Na, Zhu, Ling, Guan, Gongchang, Liu, Peng, Zhang, Yong, Wang, Junkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070885/
https://www.ncbi.nlm.nih.gov/pubmed/33888540
http://dx.doi.org/10.1136/bmjdrc-2020-001884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070885/
https://www.ncbi.nlm.nih.gov/pubmed/33888540
http://dx.doi.org/10.1136/bmjdrc-2020-001884

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